Search results for "Rosmarinus officinalis L."

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Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components

2012

In this study, Rosmarinus officinalis L. essential oil and three of its main components 1,8-cineole (27.23%), α-pinene (19.43%) and β-pinene (6.71%) were evaluated for their in vitro antibacterial activities and toxicology properties. R. officinalis L. essential oil possessed similar antibacterial activities to α-pinene, and a little bit better than β-pinene, while 1,8-cineole possessed the lowest antibacterial activities. R. officinalis L. essential oil exhibited the strongest cytotoxicity towards three human cancer cells. Its inhibition concentration 50% (IC50) values on SK-OV-3, HO-8910 and Bel-7402 were 0.025‰, 0.076‰ and 0.13‰ (v/v), respectively. The cytotoxicity of all the test sampl…

Pharmaceutical ScienceRosmarinusAnalytical Chemistrylaw.inventionchemistry.chemical_compoundlawDrug DiscoveryFood scienceCytotoxicityBicyclic Monoterpenesbiologyantibacterial activities18-cineoleAnti-Bacterial AgentsChemistry (miscellaneous)α-pineneOfficinaliscytotoxicityMolecular MedicineAntibacterial activityCell SurvivalMicrobial Sensitivity TestsRosmarinus officinalis L.Articlelcsh:QD241-441Bridged Bicyclo CompoundsInhibitory Concentration 50lcsh:Organic chemistryCell Line TumorBotanyOils Volatile<em>Rosmarinus officinalis </em>L.; 18-cineole; α-pinene; β-pinene; antibacterial activities; cytotoxicityHumansPhysical and Theoretical ChemistryIC50Essential oilEucalyptolBacteriaPlant ExtractsOrganic ChemistryCyclohexanolsbiology.organism_classificationAntineoplastic Agents PhytogenicRosmarinusβ-pineneEucalyptolchemistryMonoterpenesDrug Screening Assays AntitumorHuman cancerMolecules; Volume 17; Issue 3; Pages: 2704-2713
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Impact of the Extraction Method on the Chemical Composition and Antioxidant Potency of Rosmarinus officinalis L. Extracts

2023

Rosmarinus officinalis L. is a dietary source that produces polyphenols as secondary metabolites. These natural compounds with potent antioxidant abilities are increasingly recommended as a supplement to inhibit oxidative stress. In the current work, we evaluated the impact of the extraction method on the chemical composition of R. officinalis extract, especially on the content of carnosic (CA) and rosmarinic (RA) acids using UPLC-MS-DAD as well as on their antioxidant potency. Four extracts of Tunisian rosemary were obtained from non-conventional extraction techniques:ultrasound-assisted extraction (UAE),supercritical extraction (SFE) and UAE and SFE combined ((UAE-SFE(I), UAE-SFE(II)). Th…

sonication<i>Rosmarinus officinalis</i> L.antioxidantUPLC-MS-DAD analysisEndocrinology Diabetes and MetabolismRosmarinus officinalis L UPLC-MS-DAD analysis antioxidant sonication supercritical extractionsupercritical extractionMolecular BiologyBiochemistry
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